Multiple myeloma-associated light chain amyloidosis presenting as verrucous lingual masses.

Sir, Multiple myeloma is a monoclonal B-cell neoplasm, which is characterized by autonomous proliferation of immunoglobulin-secreting plasma cells, capable of synthesizing amyloidogenic light chains (AL). AL amyloidosis is characterized by extracellular deposition of eosinophilic, homogeneous, amorphous material composed of fibrillary protein, containing light chain fragments (1). The oral clinical features of patients with AL amyloidosis include papules, nodules, plaques and macroglossia (2). To our knowledge, verrucous masses on both lateral sides of the tongue, without macroglossia, have not been described in the literature so far. Herein, we report such a case.